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KMID : 0370219970410050602
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Yakhak Hoeji
1997 Volume.41 No. 5 p.602 ~ p.606
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Preparation and Evaluation of Coated-Peonja Dry Elixir for Masking the Bitterness
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김종국/Kim CK
최한곤/Choi HG
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Abstract
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Peonjahwan composed of crude herb, and materials and tissue of animals is a considerably bitter and poorly water-soluble oriental medicine for the treatment of hepatitis. Peonja dry elixir and Eudragit-coated peonja dry elixir were prepared using spray-dryer to mask the bitterness and enhance the release of ingredients from peonjahwan. The bitterness of peonja dry elixir and Eudragit-coated peonja dry elixir reduced to 1/2 and 1/4 of that from peonja powder, respectively. Furthermore, the release rate of bound bilirubin from dry elixir was significantly higher than that from peonja powder.
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